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The link between family history and risk of type 2 diabetes is not explained by anthropometric, lifestyle or genetic risk factors: the EPIC-InterAct study

DiabetologiaPublished 28 September 2012Open access
Robert A. Scott, Claudia Langenberg, Stephen J. Sharp, Paul W. Franks, Olov Rolandsson, Dagmar Drogan
Citations337
SJR quartileQ1
SJR score3.62
SNIP2.67
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TL;DR

Prominent lifestyle, anthropometric and genetic risk factors explained only a marginal proportion of the excess risk associated with family history, highlighting the fact that family history remains a strong, independent and easily assessed risk factor for type 2 diabetes.

Abstract

Prominent lifestyle, anthropometric and genetic risk factors explained only a marginal proportion of the excess risk associated with family history, highlighting the fact that family history remains a strong, independent and easily assessed risk factor for type 2 diabetes. Discovering factors that will explain the association of family history with type 2 diabetes risk will provide important insight into the aetiology of type 2 diabetes.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology