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The universal dinucleotide asymmetry rules in DNA and the amino acid codon choice

Journal of Molecular EvolutionPublished 1 July 1981
Ruth Nussinov
Citations46
SJR quartileQ1
SJR score0.82
SNIP0.55

TL;DR

This paper shows that this assymmetric behavior does not stem from the coding requirements of the DNA, and shows some codon patterns in prokaryotic and eukaryotic genomes which came up in the course of this work.

Abstract

Natural DNA sequences were recently found to contain distinct nearest neighbor patterns. Hetero-dinucleotides were demonstrated to appear consistently more (less) than their mirror-image counterparts. This paper shows that this asymmetric behavior does not stem from the coding requirements of the DNA. It also shows some codon patterns in prokaryotic and eukaryotic genomes which came up in the course of this work.

Keywords

Biochemistry, Genetics and Molecular Biology