Katalytische enantioselektive 1,3‐dipolare Cycloaddition von Azomethinyliden und Alkenen: der direkte Weg zu enantiomerenangereicherten mehrfach substituierten Prolinderivaten
Angewandte ChemiePublished 19 September 2005
Carmén Nájera, José M. Sansano
Citations89
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Abstract
Ohne Umwege: Die asymmetrische 1,3-dipolare Cycloaddition von Azomethinyliden (aus Iminen A; EWG=elektronenziehende Gruppe) und elektrophilen Alkenen B unter Verwendung substöchiometrischer Mengen an chiralen Metallkomplexen ermöglicht auf direktem Weg die stereoselektive Herstellung von Pyrrolidin- oder Prolinderivaten C. Anhand aktueller Veröffentlichungen werden die für diese Reaktion wirksamen Ligand-Metallkation-Paare beleuchtet.
Keywords
Chemistry
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