Novel <i>Cinchona</i>‐Aminobenzimidazole Bifunctional Organocatalysts
Advanced Synthesis & CatalysisPublished 1 December 2009
Lei Zhang, Myoung‐Mo Lee, Soomi Lee, Jihye Lee, Maosheng Cheng, Byeong‐Seon Jeong
Citations55
SJR quartileQ1
SJR score0.93
SNIP0.92
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Abstract
Abstract Efficient Cinchona ‐derived chiral 2‐aminobenzimidazole catalysts were prepared by the coupling of 5,7‐bis(trifluoromethyl)‐2‐chlorobenzimidazole with C(9 S )‐aminodihydroquinine or C(9 R )‐aminodihydroquinidine and successively applied to the Michael addition of dimethyl malonate to nitroolefins as very efficient chiral Lewis acid bifunctional organocatalysts (up to >99% ee ).
Keywords
Chemistry
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