The cortico-nigral projection: reduced glutamate content in the substantia nigra following frontal cortex ablation in the rat
Brain ResearchPublished 1 November 1984
Johannes Kornhuber, Jin-Soo Kim, Malte Kornhuber, H. H. Kornhuber
Citations132
SJR quartileQ2
SJR score0.85
SNIP0.72
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TL;DR
The results suggest that glutamate is a transmitter in the cortico-nigral fibre tract and that glutamic acid in the ipsilateral compares with the contralateral substantia nigra and both the glutamate and GABA levels in the hippocampus remain unchanged.
Abstract
Unilateral ablation of the frontal cortex results in a significant reduction (19.5%) of glutamic acid in the ipsilateral compared with the contralateral substantia nigra. The GABA level in the substantia nigra and both the glutamate and GABA levels in the hippocampus remain unchanged. The results suggest that glutamate is a transmitter in the cortico-nigral fibre tract.
Keywords
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