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The Role of Leptin in the Control of Body Weight

Nutrition ReviewsPublished 1 October 2002Open access
Rudolph L. Leibel
Citations203
SJR quartileQ1
SJR score1.86
SNIP2.02
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TL;DR

Physiologic responses to high and low leptin concentrations are strikingly asymmetrical, where high concentrations often produce minimal effects, whereas low concentrations provoke strong counterregulatory responses.

Abstract

Physiologic responses to high and low leptin concentrations are strikingly asymmetrical. High concentrations often produce minimal effects, whereas low concentrations provoke strong counterregulatory responses. A model and rationale for the physiology is presented.

Keywords

MedicineNeuroscience