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Brain Serotonin2 Receptors in Major Depression

Archives of General PsychiatryPublished 1 September 2000
Lakshmi N. Yatham, Peter F. Liddle, I‐Shin Shiah, Gayle Scarrow, Raymond W. Lam, Michael J. Adam
Citations172

TL;DR

Depressed patients had significantly lower 5-HT(2) receptor binding potential in frontal, temporal, parietal, and occipital cortical regions, according to statistical parametric mapping and region of interest analyses.

Abstract

This study suggests that brain 5-HT(2) receptors are decreased in patients with major depression.

Keywords

MedicineNeuroscience