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Genetic Liability for Bipolar Disorder Is Characterized by Excess Frontal Activation in Response to a Working Memory Task

Biological PsychiatryPublished 21 June 2008
Dominique Drapier, Simon Surguladze, Nicolette Marshall, Katja Schulze, Adele Fern, Mei‐Hua Hall
Citations89
SJR quartileQ1
SJR score4.68
SNIP2.24

TL;DR

Left prefrontal hyperactivation during working memory is associated with genetic liability for bipolar disorder and represents a potential neurobiological endophenotype for the illness.

Abstract

Left prefrontal hyperactivation during working memory is associated with genetic liability for bipolar disorder and represents a potential neurobiological endophenotype for the illness.

Keywords

MedicineNeuroscience